. Author manuscript; available in PMC: 2013 Mar 16.

Published in final edited form as: J Org Chem. 2012 Mar 6;77(6):2966–2970. doi: 10.1021/jo202686p

Table 3.

Scope of Substituted Benzyl Chlorides.


entry	product	time	yield (%)
1	1b	5 h	58
2	1c	3 h	77
3	1d	3 h	76
4	1e	7 h	62
5	1f	5 h	56 (72)^a
6	1g	3 h	49
7	1h	7 h	80
8	1i	6 h	0
9	1j	4 h	73
10	1k	2.5 h	59
11	1l	24 h	34

Benzyl chloride (2.0 mmol), potassium cyclopropyltrifluoroborate (3.5 mmol), Pd₂(dba)₃ (0.1 mmol), RuPhos (0.2 mmol), K₂CO₃ (4.0 mmol), toluene/H₂O 19:1 (0.1 M), 120 °C.

Reaction performed on 1 g scale.