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. Author manuscript; available in PMC: 2013 Mar 16.
Published in final edited form as: J Org Chem. 2012 Mar 6;77(6):2966–2970. doi: 10.1021/jo202686p

Table 4.

Scope of Potassium Alkoxymethyltrifluoroborates.

graphic file with name nihms361774u4.jpg
entry product time yield (%)
1 graphic file with name nihms361774t14.jpg 2a 24 h 66
2 graphic file with name nihms361774t15.jpg 2b 16 h 62
3 graphic file with name nihms361774t16.jpg 2c 3 h 45
4 graphic file with name nihms361774t17.jpg 2d 5 d 45
5 graphic file with name nihms361774t18.jpg 2e 3 d 40
6 graphic file with name nihms361774t19.jpg 2f 4 d 42
7 graphic file with name nihms361774t20.jpg 2g 20 h 29

Benzyl chloride (2.0 mmol), potassium alkoxymethyltrifluoroborate (3.5 mmol), PEPPSI (0.1 mmol), K2CO3 (4.0 mmol), toluene/H2O 19:1 (0.1 M), 120 °C.