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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Feb 2;32(4):955–961. doi: 10.1161/ATVBAHA.111.241034

Figure 3. Injury-induced proliferation is increased in wild-type arteries compared to S1PR3-null arteries.

Figure 3

Wild-type (wt) and S1PR3-null iliac-femoral arteries were denuded and injected with BrdU (30 μg/g body weight) at 17, 8 and 1 hour prior to sacrifice at the indicated time points. Arteries were perfusion-fixed and tissue sections stained with anti-BrdU (Roche). The number of positive cells in media (A) and intima (B) was quantitated by counting multiple sections that were 250 μm apart. Data (mean +/− SEM, N=7–13 animals per group) are presented as percent BrdU positive cells. *P<0.05