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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Dec 21;260(1):1–16. doi: 10.1016/j.taap.2011.12.014

Table 2.

Summary of the effect of surface treatments on Ni particulate uptake

Metal Charge
(mV)
Particle
size
(μm)
Concentrati
on(μg/ml)
Concentration
(μg/cm2 growth
area)
Treatme
nt time
(hours)
Cells with
endocytized
particles
(%)
Untreated crystalline NiS −27 2.37 10 1.78 24 29.2
Untreated amorphous NiS +9 1 10 1.78 24 4.8
Solvent-washed crystalline
NiS
NA 2.07 10 1.78 24 33.3
LiAlH4 reduced crystalline
NiS
NA 3.76 10 1.78 24 51
Solvent-washed
amorpohous NiS
NA 2.66 10 1.78 24 9.9
LiAH4-reduced amorpohus
NiS
NA 2.26 10 1.78 24 27.7

CHO cells were treated with particles for 24 hours.

Heck and Costa 1982b