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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Jan 19;32(4):979–987. doi: 10.1161/ATVBAHA.111.244053

Figure 2.

Figure 2

miR-92a targeting of the 3′ UTRs of KLF4 and KLF2. A: Evolutionarily-conserved putative miR-92a binding sites in 3′ UTRs of KLF4 and KLF2. B: Reduced luciferase activity in HEK293 cells overexpressing miR-92a mimetics or miR-92a precursors following insertion of the full-length 3′UTRs cloned from human KLF4 and KLF2 (n=4-5). Ctl plasmids express wild-type firefly luciferase without 3′ UTR insertions. Data represent mean ± SEM. *p < 0.05.