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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Jan 19;32(4):979–987. doi: 10.1161/ATVBAHA.111.244053

Figure 3.

Figure 3

miR-92a negatively regulates KLF4 and KLF2 through the seed-pairing sequence(s) in the 3′UTR binding site(s). A: Schematic representation of the luciferase vectors containing the full-length 3′ UTR(s) of KLF4 and KLF2 and mutation(s) in the miR-92a seed-pairing site(s). B: Reduced luciferase activity in HEK293 cells overexpressing miR-92a precursors following insertion of the mutant clones (n=3-5). Data represent mean ± SEM. *p < 0.05.