Table 3.

Identification of Differentially Expressed Phosphorylated Proteins of the MIA PaCa-2 cells Treatment with CP-320626 by MALDI-TOF/TOF MS

Accession Number	Protein name	Idenfication method	Sequence Coverage	Caculated MW/pI	Post-translational modification	Functional annotation	Associated diseases	Reference
P43403	Tyrosine-protein kinase ZAP-70	PMF	17%	70796/7.78	Protein kinase	T-cell development, activation and induces TCR-mediated signal transduction	Selective T-cell defect	Ref. (33–36)
P47755	F-actin-capping protein subunit alpha-2	PMF and MS/MS	18%	33157/5.57	Phosphorylated protein	Regulate cell motility	Glioblastomas, breast cancer and human renal cell carcinoma	Ref. (37–40)
Q969J3	Loss of heterozygosity 12 chromosomal region 1 protein	PMF	43%	22322/5.97	Phosphorylated protein	T cell receptor signaling	Childhood acute lymphoblastic leukemia	Ref. (41–43)
P63241	Eukaryotic translation initiation factor 5A-1	PMF and MS/MS	40%	17049/5.08	Phosphorylated protein	Cell cycle progression, mRNA decay, stress response and maintenance of cell wall integrity	Aberrant proliferation in intraepithelial neoplasia of the vulva	Ref. (44–46)