Figure 3. Evi is required for proliferation and survival of glioblastoma cell lines.

1. Viability of RNAi transduced U87MG cells, A172, U251MG cells and T98G was determined by CellTiter-Glow assay and revealed reduced viability of Evi-RNAi transduced cells compared to control cells. β-catenin silencing had significant effect on viability of U787MG and U251MG cells. Evi and β-catenin silencing had no significant effect on proliferation of T98G cells (*p < 0.05).
2. Evi and β-catenin silencing caused reduced colony formation in U251MG cells. Representative example of three-independent experiments is shown (right). Data are expressed as mean ± SD of three-independent experiments (*p < 0.05).