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. 2012 Jan;4(1):38–51. doi: 10.1002/emmm.201100186

Figure 4. Depletion of Evi induces apoptosis in glioblastoma-derived cancer stem-like cells.

Figure 4

  1. Neurosphere shape and size was disturbed after Evi silencing. Scale bar: 100 µm.
  2. Reduction in cell number compared to control transfected spheres 7 days after infection (**p < 0.01; ***p < 0.001).
  3. Lentiviral shRNA silencing of Evi expression in NCH421k and NCH644 cells led to an increase in the sub-G1 fraction (*p < 0.05; **p < 0.01).
  4. Representative graphs of cell cycle distribution. Data are expressed as mean ± SD of three-independent experiments.