Figure 2.

Fluctuation in the level of bound receptor: (a) fluctuations about the steady-state BMP : receptor (BR) owing to stochasticity both in the presence (green line, Cv-2 = 85) and in the absence (red line, Cv-2 = 0) of Cv-2 are shown. Owing to slow-binding kinetics between BMP and its receptor, BR fluctuations exhibit long durations (red) that are shortened when binding between BMP and Cv-2 (green) is included. (b) Probability density functions for BR in the presence (green bars, Cv-2 = 85) and absence of Cv-2 (red bars, Cv-2 = 0).