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. 2012 Feb 27;109(11):4320–4325. doi: 10.1073/pnas.1119908109

Fig. 4.

Fig. 4.

Difference between KHK-A and KHK-C. (A and B) Kinetic analysis of recombinant human KHK-C (A) and KHK-A (B) for d-fructose. Nonlinear regression fit to Michaelis-Menten equation (n = 4). (C and D) ATP consumed by 100 ng or 1,000 ng of KHK-C (C) or KHK-A (D) with 5 mM fructose. No fructose was used as control. Data represent means. **P < 0.01, ***P < 0.001 vs. control. (E–G) Quantitative RT-PCR. Relative comparison of expressions of KHK-C (E) and KHK-A (F) in various organs (n = 2–3) and in liver (G, n = 6) from WT mice.