Fig. 3.

Reduced ATM kinase activity causes neuron and glial cell death in the adult brain. Shown are representative paraffin sections of WT, ATM⁸/+, and ATM⁸ brains after 7 d (A–C) or 17 d (D–F) at 25 °C. Holes are indicated by arrows. Images are shown of the same region of the brain and at the same magnification, with anterior at the top. Full brain sections are shown in Fig. S1. Shown are representative immunofluorescence images of ATM⁸ brains stained for Repo and Casp^Act (G–I) or Elav and Casp^Act (J–L).