Table 1. Amphiphilic HA derivatives for imaging or drug delivery.
Carrier | Additional hydrophilic substituent | Hydrophobic moiety | Structure of hydrophobic moiety | Drug | Ref. |
---|---|---|---|---|---|
HA-g-TDA | - | TDA | - | [142] | |
HA-g-CA | -/PEG | CA | - | [143-144, 148] | |
HA-g-PEG-PCL | PEG | PCL | DOX | [145] | |
HA-g-PEG-PLGA | PEG | PLGA | DOX | [141] | |
HA-g-PLGA | - | PLGA | DOX | [146] | |
HA-g-Oligo(VBODENA) | - | Oligo(VBODENA) | PTX | [147] | |
HA-b-PBLG | - | PBLG | DOX, DTX | [150-151] |
Abbreviations: TDA = tertradecylamine; CA = 5b-cholanic acid; PCL = poly(caprolactone); PLGA = poly(lactic-co-glycolic acid); PEG = polyethylene glycol); oligo(VBODENA) = oligo(2-(4-(vinylbenzyloxy)-N, N-diethylnicotinamide)); and PBLG = poly(γ-benzyl-glutamate).