Figure 1.

Correlations between behavioral endophenotypes and brain region 5-HT levels in 40,XY and 39,X^Y*O mice (black and white circles, respectively). There was a positive correlation between hippocampal 5-HT levels and the highest break point achieved in a PR task (a), a positive correlation between striatal 5-HT levels and a homecage activity measure (b), and a negative correlation between striatal 5-HT levels and latency to enter a relatively non-aversive environment from an aversive one in the light–dark box test (c).