Table 1.

Characteristics of trials included in analysis.

Reference	N of participant, Intervention/placebo groups	Inclusion criteria	Domperidone dose	Domperidone duration of treatment	Outcome	Outcome assessment
Petraglia et al. [19] (1985)	9/8	Premiparous mothers of term infants with insufficient lactationa 2 weeks post partum	30 mg/day	10 days	Daily breast milk yield, before and after treatment, mL/day	By weighing the infants before and after breastfeeding using an electronic integrating scale and summarizing the single milk yields for the day
Da Silva et al. [8] (2001)	7/9	Mothers of preterm infants with low milk productionb	30 mg/day	7 days	Daily breast milk volume, before and after treatment, mL/day	Mechanically expressed breast milk by using a double collecting pump
Campbell-Yeo et al. (2010) [20]	21/24	Mothers of preterm infants (<31 weeks gestation) with lactation failurec ≥3 wks after delivery	30 mg/day	14 days	Daily breast milk volume, before and after treatment, mL/day	Mechanically expressed breast milk by using a double collecting system

^ainsufficient lactation defined as milk yields at least 30% lower than those reported as normal

^blow milk production defined as not meeting the infant's daily oral feeding requirements

^clactation failure defined as not of the following: a decreasing milk supply by >30% from peak volume based on maternal count or inability to meet the daily nutritional intake of the infant.