Table 3.
Characteristics of the post-chemotherapy patients who had ovarian tissue cryopreservation.
| No. | Pathology | Chemotherapy | Age (months) | D/mm2 (RO) | D/mm2(LO) | Cryopreserved fragments No. |
|---|---|---|---|---|---|---|
| 1 | Wilms tumor | Vincristine, AMD | 19 | 268.63 | 49.69 | 4 |
| 2 | Wilms tumor | Vincristine, AMD | 48 | — | — | 1 |
| 3 | Acute myeloide leukaemia | ICE, AVE, HAM, ARA-C | 70 | 112.84 | 56.23 | 19 |
| 4 | Acute lymphoblastic leukaemia | Vincristina, cyclophosphamide, methotrexate | 91 | 40.61 | 92.09 | 24 |
| 5 | Acute lymphoblastic leukaemia | AIEOP 9502 | 170 | 12.03 | 22.62 | 67 |
| 6 | Hodgkin lymphoma | COPP/ABV | 81 | 59.38 | — | 10 |
| 7 | Hodgkin lymphoma | COPP/ABV + IEP-OPPA | 134 | 9.96 | 11.05 | 31 |
| 8 | Hodgkin lymphoma | COPP/ABV | 131 | 7.18 | 13.90 | 42 |
| 9 | Hodgkin Lymphoma | ABVD | 150 | 12.64 | 29.98 | 13 |
| 10 | Hodgkin Lymphoma | COPP/ABV | 165 | 5.66 | 8.87 | 55 |
| 11 | Hodgkin lymphoma | COPP/ABV | 166 | 19.19 | 43.34 | 14 |
| 12 | Hodgkin lymphoma | COPP/ABV | 175 | 5.55 | 10.81 | 13 |
| 13 | Hodgkin lymphoma | IEP/IOPPA | 177 | 30.33 | 31.57 | 21 |
| 14 | Hodgkin lymphoma | COPP/ABV | 197 | 6.80 | 11.99 | 8 |
| 15 | Hodgkin lymphoma | COPP/ABV | 215 | 5.08 | 7.67 | 49 |
| 16 | Synovial sarcoma | IFO, AMD | 154 | 15.12 | 14.95 | 47 |
| 17 | Ewing sarcoma | ISG/SSG IV | 170 | 8.04 | 7.82 | 71 |
| 18 | Acute myeloide leukaemia | Idarubicin, etoposide, citrabina | 180 | 3.67 | 4.56 | 20 |
| 19 | Acute lymphoblastic leukaemia | Vincristine, daunomycin, predmisone | 183 | 9.61 | 10.45 | 12 |
| 20 | Acute lymphoblastic leukaemia | Unspecified | 192 | 19.37 | 12.18 | 33 |
| 21 | Acute lymphoblastic leukaemia | Vincristine, cyclophosphamide, methotrexate | 209 | 12.02 | 11.36 | 53 |
| 22 | Medulloblastoma | Vincristine | 199 | 9.85 | 10.19 | 25 |
| 23 | Peripheral neuroectodermal tumor | IFO, etoposide, thiotepa, adriamycin melphalan | 212 | 0 | 0 | 61 |
No. 1–7 premenarcheal patients; No. 8–23 postmenarcheal patients.
D/mm2: follicle density per mm2.
RO: right ovary; LO: left ovary.
AMD: Actinomycin D; ICE: Idarubicin, Etoposide, Cytarabin; HAM: Mitoxantrone; ARA-C: Citosinarabinoside; AIEOP9502.
Protocol: Vincristine, Daunomycin, Predmisone, Asparaginase, Cyclophosphamide, 6-Mercaptopurine, Methotrexate, Adriamycin,
Dexamethasone, Cyclophosphamide, Citosinarabinoside, 6-Thioguanina; COPP/ABV: Vincristine, Procarbazine,
Cyclophosphamide, Prednisone, Adriamycin, Vinblastine, Bleomycin; IEP-OPPA: Ifofosfamide, Etoposide, Prednisone, Vincristine,
Procarbazine, Prednisone, Adriamycin; ABVD: Adriamycin, Bleomycin, Vincristine, Doxorubicin; IFO: Ifofosfamide; ISG/SSG IV.
Protocol: Vincristine, Adriamycin, Ifosfamide, Cyclophosphamide, Etoposide.