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TNF-α productive capacity of splenocytes in response to their stimulation with LPS in wild-type (WT) and IL-6 knockout (IL-6−/−) mice in sham animals (group S), after an isolated femoral fracture (group Fx) and after the combination of a femoral fracture and hemorrhage (group TH-Fx). *stat. significance (P < 0.05) S vs. Fx and TH-Fx, #stat. significance (P < 0.05) Fx versus. TH-Fx, $stat. significance (P < 0.05) WT vs. IL-6−/−.
