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. 2012 Mar 15;2(2):e000642. doi: 10.1136/bmjopen-2011-000642

Table 1.

Characteristics of a randomised sample of 842 question–answer pairs in the RELIS public database 1995–2006

Period 1995–2000 2001–2006 p Value
Questions, n 312 530
 Drugs involved, category: % One: 49 One: 45 0.434§
Two: 19 Two: 22
Three or more: 32 Three or more: 34*
 Judgemental questions, n (%) 207 (66) 399 (75) 0.005§
 Patient-related questions, n (%) 170 (54) 379 (72) <0.001§
Answers, n 312 530
 Literature search, type: % None: 3 None: 2 0.315§
Simple: 43 Simple: 40
Advanced: 54 Advanced: 58
 Reference to RELIS database, n (%) 39 (13) 164 (31) <0.001§
 References, median (average) 3 (4) 4 (5) 0.100
 Days, median (average) 2 (8.4) 1 (5.0) 0.001
*

The total number exceeds 100% because of rounding off to the nearest whole number.

Simple literature search included monographs (eg, Martindale, Summary of Product Characteristics), advanced literature search included articles (eg, databases like Medline and Embase).

Answer time is influenced by some extreme outliers (>100 days) and choice of deadline for answer (‘not important’ is an option).

§

χ2 Test for contingency tables.

Mann–Whitney U test for two independent samples.