Table 1.
Characteristic | pH1N1 wave 1 versus wave 2 |
pH1N1 versus seasonal influenza |
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pH1N1 wave 1 (n=58) | pH1N1 wave 2 (n=118) | p Value | pH1N1 total (n=176) | Seasonal, (n=200) | p Value | |
Sex, male, n (%) | 35 (60) | 72 (61) | 0.93 | 107 (61) | 108 (54) | 0.18 |
Age, years, median (IQR) | 6.4 (3.4–10.1) | 6.5 (2.9–11.4) | 0.81 | 6.5 (3.0–10.6) | 3.3 (1.4–7.8) | <0.01 |
Age group, years, n (%) | ||||||
<2 | 8 (14) | 23 (19) | 0.35 | 31 (18) | 74 (37) | <0.01 |
2 to <5 | 13 (22) | 24 (20) | 0.75 | 37 (21) | 54 (27) | 0.18 |
≥5 | 37 (64) | 71 (60) | 0.64 | 108 (61) | 72 (36) | <0.01 |
Admitted to ICU | ||||||
No. (%) of children | 12 (21) | 20 (17) | 0.36 | 32 (18) | 31 (15) | 0.49 |
Age, years, median (IQR) | 5.8 (3.2–7.3) | 9.2 (5.4–11.4) | 0.13 | 7.3 (4.0–10.6) | 3.6 (1.5–9.7) | 0.02 |
Required mechanical ventilation | ||||||
No. (%) of children | 7 (12) | 11 (9) | 0.57 | 18 (10) | 19 (10) | 0.81 |
No. (%) of children admitted to ICU | 7 (58) | 11 (55) | 0.85 | 18 (56) | 19 (61) | 0.69 |
Required supplemental oxygen | ||||||
No. (%) of children | 26 (47) | 33 (28) | 0.01 | 59 (34) | NA | NA |
Duration of oxygen, days, median (IQR) | 4 (2–6) | 3 (2–7) | 0.73 | 3 (2–6) | NA | NA |
Length of stay, days, median (IQR) | ||||||
In hospital | 4 (2–6) | 3 (2–5) | 0.06 | 3 (2–5) | 4 (2–7) | 0.12 |
In ICU | 3.5 (2.5–17) | 2 (1.5–5) | 0.08 | 3 (2–8) | 2 (1–5) | 0.24 |
Antiviral therapy, n (%) | 11 (19) | 97 (82) | <0.01 | 108 (61) | 16 (8) | <0.01 |
Bold values are significantly different as defined by a p value <0.05.
ICU, intensive care unit; pH1N1, pandemic H1N1.