Fig. 4.

Establishment times and selection coefficients of real and inferred mutant haplotypes. Establishment times of inferred haplotypes were paired with the establishment times of real haplotypes reaching a frequency of q₀. Paired event times are shown for the first (red), second (green), third (blue) and fourth (black) mutants inferred by the method. Each pair is shown by a rectangle, the height/width ratio of which is equal to the ratio between the real and inferred mutant haplotype fitness. Data are shown for σ₀=0.05 and U=1×10⁻⁷.