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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Hypertension. 2012 Feb 27;59(4):869–876. doi: 10.1161/HYPERTENSIONAHA.111.182071

Figure 1. Slow-pressor Ang-II hypertension is prevented in mice with null mutations in EP1R or COX-1 but not COX-2.

Figure 1

A) Summary of MAP before, during and after 2 wk slow-pressor Ang-II infusions in WT (n=5) and EP1R−/− (n=7) mice. B) MAP throughout slow-pressor Ang-II in WT (n=7), COX-2−/− (n=4) and COX-1−/− (n=5) mice. *p<0.05 vs. baseline (WT in panels A and B; COX-2 in panel B); †p<0.05 vs. WT or COX-2−/−. Arrow indicates start of Ang-II infusions.