Table 1.
Baseline (1996–97) characteristics by microalbuminuria/kidney function categories
| Normal & no MA | Normal & MA | Pre-KD & no MA | Pre-KD & MA | CKD & no MA | CKD & MA | All | |
|---|---|---|---|---|---|---|---|
| n | 1011 | 140 | 1247 | 271 | 424 | 198 | 3291 |
| Age | 76 (4) | 77 (5) | 78 (5) | 79 (5) | 79 (5) | 80 (6) | 78 (5) |
| Gender (female) | 667 (66%) | 86 (61%) | 707 (57%) | 131 (48%) | 278 (66%) | 101 (51%) | 1970 (60%) |
| Race (black) | 203 (20%) | 40 (29%) | 159 (13%) | 44 (16%) | 56 (13%) | 32 (16%) | 534 (16%) |
| BMI (kg/m2) | 26.3 (4.3) | 26.0 (4.5) | 27.3 (4.8) | 26.8 (4.7) | 27.4 (4.9) | 27.1 (4.7) | 26.9 (4.6) |
| Ever smoked | 487 (49%) | 80 (58%) | 637 (52%) | 159 (60%) | 211 (51%) | 112 (58%) | 1686 (51%) |
| Diabetes | 119 (12%) | 42 (30%) | 127 (10%) | 92 (34%) | 55 (13%) | 49 (25%) | 484 (15%) |
| Hypertension | 400 (40%) | 94 (67%) | 572 (46%) | 177 (66%) | 242 (57%) | 154 (78%) | 1639 (50%) |
| Antihypertensives | 449 (44%) | 92 (66%) | 692 (56%) | 191 (71%) | 304 (72%) | 170 (86%) | 1898 (58%) |
| Cholesterol (mmol/L) | 5.22 (0.93) | 5.17 (1.03) | 5.22 (1.03) | 5.04 (1.06) | 5.32 (1.03) | 5.32 (1.24) | 5.22 (1.02) |
| CRPa (mg/L) | 1.96 (0.93, 4.25) | 1.96 (0.84, 4.90) | 2.52 (1.16, 5.10) | 3.11 (1.53, 6.77) | 2.54 (1.25, 5.62) | 3.74 (1.82, 7.31) | 1.96 (0.93, 4.25) |
| ECG AF | 15 (2%) | 10 (7%) | 45 (4%) | 31 (11%) | 15 (4%) | 16 (8%) | 132 (4%) |
| ECG LVH | 33 (3%) | 12 (9%) | 64 (5%) | 34 (14%) | 19 (5%) | 24 (13%) | 186 (6%) |
| Prevalent disease | |||||||
| Stroke | 41 (4%) | 7 (5%) | 63 (5%) | 27 (10%) | 31 (7%) | 31 (16%) | 200 (6%) |
| MI | 63 (6%) | 11 (8%) | 126 (10%) | 54 (20%) | 64 (15%) | 48 (24%) | 366 (11%) |
| CHF | 33 (3%) | 14 (10%) | 97 (8%) | 43 (16%) | 54 (13%) | 58 (29%) | 299 (9%) |
| eGFR-MDRD | 95 (19) | 98 (20) | 80 (15) | 80 (15) | 51 (8) | 43 (14) | 79 (23) |
| Cystatin C (mg/L) | 0.88 (0.08) | 0.90 (0.08) | 1.16 (0.15) | 1.23 (0.19) | 1.47 (0.37) | 1.95 (0.82) | 1.16 (0.39) |
| ACRa (mg/g) | 7 (4, 11) | 55 (40, 103) | 7 (4, 12) | 72 (46, 154) | 8 (5,14) | 119 (62, 363) | 7 (4, 11) |
Data are presented as either mean or percentage, unless a [median (interquartile range)]; BMI = body mass index; CRP = C-reactive protein; ECG = electrocardiogram; AF = atrial fibrillation; LVH = left ventricular hypertrophy; MI = myocardial infarction; CHF = congestive heart failure; ACR = urine microalbumin/creatinine ratio.