TABLE 2.
Cytoplasmic pSTAT3 associates with tumor size (T-stage), patient status, EGFR phosphorylation, heparanase expression, and cellular localization
Values designates the number of patients, and values in parentheses designate the percent of the total in that group.
| pSTAT3 localization | Cytoplasmic pSTAT3 | Nuclear pSTAT3 | Total |
|---|---|---|---|
| T-Stage (p = 0.007) | |||
| 0–2 | 0 | 24 (36) | 24 |
| 3–4 | 14 (100) | 43 (64) | 57 |
| Total | 14 | 67 | 81 |
| Status (p = 0.04) | |||
| Dead | 11 (79) | 31 (46) | 42 |
| Alive | 3 (21) | 36 (54) | 39 |
| Total | 14 | 67 | 81 |
| pEGFR (p = 0.006) | |||
| Negative | 0 | 18 (37) | 18 |
| Positive | 14 (100) | 30 (63) | 44 |
| Total | 14 | 48 | 62a |
| Heparanase extent (p = 0.03) | |||
| Low | 1 (7) | 21 (36) | 22 |
| High | 13 (93) | 37 (64) | 50 |
| Total | 14 | 58 | 72b |
| Heparanase localization (p = 0.03) | |||
| Cytoplasmic | 10 (71) | 21 (36) | 31 |
| Nuclear | 4 (29) | 37 (64) | 41 |
| Total | 14 | 58 | 72b |
a Data of 19 patients were missing.
b Data of nine patients were missing.