FIGURE 4.
Quaternary structure organization of DgAS (PDB code 3UCQ). Panel A, visualization of the DgAS dimer. The protomers are symmetry-related following a 2-fold crystallographic symmetry. Panel B, structural superimposition of DgAS (purple) and NpAS (PDB code 1G5A (18)) (green) monomeric units. Structural elements involved in the dimeric interface of DgAS involve 7 regions of domains N, A, and C. The amino acid sequences composing the 7 regions are listed. Panel C, sequence alignment of DgAS, DrAS, and NpAS. The 7 regions are shown on the alignment using the same color code as in panel B.