Figure 2.
Ablation of Nrf2 gene results in reduced adipogenesis in mouse WAT-derived preadipocytes. Preadipocytes isolated from WAT of Nrf2-/- and Nrf2+/+ mice were cultured to confluency and differentiated for 5 days using DMIRI protocol. Cells were then stained with ORO staining to visualize lipid accumulation (A) or used to measure the expression of adipogenic genes (B). n = 3; *p < 0.05 vs Nrf2+/+.