Table 2.
Myocardial gene expression array after CPB in the CO group compared to Air.
| Molecule | Air Group | CO Group | Ratio CO/Air |
|---|---|---|---|
| IL-6 | .613 | .347 | .566‡ |
| TGF-β1* | .06 | .04 | .64‡ |
| IGF-1† | .015 | .007 | .44 |
| IL-10 | .095 | .237 | 2.491‡ |
| CTF-1* | .175 | .313 | 1.8 |
Data are expressed as average with n = 3–4. CTF–1, Cardiotropin Growth Factor–1, shown to have hypertrophic and protective effects in myocytes, neurotrophic.
TGF-β1, Tumor Growth Factor-β1, multifactorial peptide, implicated as a cause of fibrosis in kidney disease and acute respiratory distress syndrome.
IGF, Insulin like growth factor, somatomedin C.
p ≤ .05.