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. 2012 Jan 5;126(2):426–435. doi: 10.1093/toxsci/kfr354

FIG. 6.

FIG. 6.

Detection of BoNT/B, C, and E activity in hiPSC-derived neurons. Seven-day cultures of hiPSC-derived neurons and RSC cells were exposed to serial dilutions of BoNT/B (A), C (B), and E (C) for 48 h in parallel. Cell lysates were analyzed for the respective SNARE target protein cleavage by Western blot, and data from three Western blots were quantified by densitometry and data plots were generated.