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. 2012 Jan 6;126(2):391–404. doi: 10.1093/toxsci/kfs002

FIG. 1.

FIG. 1.

Mouse strains and experimental designs. The B6 and B6.D2 mouse strains possess the high- and low-affinity Ahr genes, respectively (A). Two different BaP exposure protocols were followed. Protocol 1, short-term BaP exposure: Mice were exposed to 10 mg/kg/day BaP by gavage 5 days/week for 10 weeks (B). Protocol 2, long-term BaP exposure: Mice were exposed to BaP ad libitum in corn oil–soaked Western chow (BaP dissolved at 800 mg/ml in corn oil) at an estimated dose equivalent of 10 mg/kg/day for 23 weeks (C). The experimental design for the microarray experiments (D).