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Early Presence of Atherosclerotic Plaque in the Aorta of 15-Week-Old B6;Apoe−/− Versus B6.D2;Apoe−/− Mice Exposed to BaP
| Mouse strain | Thoracic aorta | Descending aorta | Thoracic + descending | Total aorta |
| B6 | 4/5 | 4/5 | 8/10 | 4/5 |
| B6.D2 | 3/5 | 0/4 | 3/9 | 3/5 |
Notes. B6, high-affinity AHR mouse strain; B6.D2, low-affinity AHR mouse strain. Mice (all male) were fed a Western diet beginning at 5 weeks of age as depicted in BaP exposure protocol 1 (Fig. 1B). n = 5 mice per experimental group.
