TABLE 4.
A Comparison of Muscle-Specific Genes Inherently Expressed in Aorta of B6 Versus B6.D2 Mice to Muscle-Specific Genes in Aorta of B6 Mice Exposed to BaP for 10 Weeks
| Gene symbol | Fold change |
AHR response element | |
| B6/B6.D2 no BaP | B6 BaP 10 week/0 week | ||
| Nppa | 25.64 | −30.53 | |
| Myh6 | 20.63 | −27.87 | |
| Ckm | 19.48 | −29.94 | |
| Sln | 17.86 | −24.07 | |
| Eef1a2 | 16.25 | −9.66 | |
| Ckmt2 | 15.66 | −20.91 | |
| Cox6a2 | 14.84 | −26.02 | |
| Myl4 | 14.26 | −16.48 | |
| Csrp3 | 13.85 | −17.14 | |
| Myl3 | 12.64 | −25.00 (−2.17) | |
| Tnnc1 | 12.54 | −22.37 | |
| Myl7 | 12.14 | −14.15 | |
| Mybphl | 11.70 | −15.03 | |
| Actc1 | 11.56 | −22.90 | |
| Mb | 11.49 | −11.33 | |
| Ttn | 10.67 | −16.52 | |
| Eno3 | 10.52 | −12.53 | |
| Ankrd1 | 9.54 | ||
| Actn2 | 9.36 | −7.83 | ✓ |
| Pgam2 | 7.83 | −8.69 | |
| Trim72 | 5.51 | −7.19 | |
| Hrc | 5.50 | −6.95 | |
| Mybpc3 | 5.33 | ||
| Myl1 | 5.08 | −8.33 (1.33) | |
| Atp2a2 | 4.66 | −7.68 | ✓ |
| Myoz2 | 4.25 | ||
| Casq2 | 4.04 | ||
| Tmod1 | 3.90 | ✓ | |
| Tcap | 3.41 | ||
| Gpc1 | 3.37 | ✓ | |
| Stard10 | 3.35 | ||
| Nrap | 3.34 | ||
| Corin | 3.30 | ||
| Des | 3.30 | ||
| Atp2a1 | −10.14 | ✓ | |
| Tnni2 | −14.34 | ✓ | |
Notes. B6, high-affinity AHR mouse strain; B6.D2, low-affinity AHR mouse strain. Values in parentheses are the fold change of the corresponding statistically significant differentially expressed genes in B6.D2 mice exposed to BaP for 10 weeks.