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. 2012 Jan 12;126(2):457–468. doi: 10.1093/toxsci/kfs003

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© The Author 2012. Published by Oxford University Press on behalf of the Society of Toxicology. For permissions, please email: journals.permissions@oxfordjournals.org.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 6. — Analysis of nanoparticle uptake with TEM. (a) A representative image obtained from an astrocyte culture treated with 10 μg/ml Ag₂₀Pep for 24 h. Frequently, cells contained large agglomerates of SNP, as depicted by arrows. Magnification 5000×. (b) A representative image obtained from a neuronal-enriched culture treated with 10 μg/ml Ag₂₀Pep for 24 h. Typically, cells do not contain any SNP agglomerates. Occasionally, individual particles or small agglomerates of SNP can be found (arrows). Magnification 3150×.