Table 1.
Variable | ICD-10 codes | Cancer in mother | Cancer in father | ||
---|---|---|---|---|---|
|
|
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Minor childrena [Nc (%)] | YA childrenb [N (%)] | Minor children [N (%)] | YA children [N (%)] | ||
Cancer site | |||||
Skin | C43-C44 | 3246 (17.4) | 2217 (12.6) | 2384 (14.9) | 1892 (13.5) |
Colorectal | C17-C21 | 1123 (6.0) | 1572 (8.9) | 1733 (10.8) | 2350 (16.8) |
Brain | C69-C72, D32-D33 | 1553 (8.3) | 1122 (6.4) | 1610 (10.0) | 1091 (7.8) |
Endocrine | C73-C75 | 1224 (6.6) | 762 (4.3) | 405 (2.5) | 282 (2.0) |
Leukemia | C90-C95 | 599 (3.2) | 371 (2.1) | 823 (5.1) | 653 (4.7) |
Non-Hodgkin disease | C82-C85, C95 | 561 (3.0) | 466 (2.6) | 856 (5.3) | 877 (6.3) |
Hodgkin disease | C81 | 467 (2.5) | 181 (1.0) | 809 (5.0) | 324 (2.3) |
Renal/bladder | C64-C68 | 300 (1.6) | 314 (1.8) | 963 (6.0) | 1170 (8.4) |
Lung | C34 | 284 (1.5) | 518 (2.9) | 614 (3.8) | 1038 (7.4) |
Head and neck | C00-C14, C30-C32 | 196 (1.1) | 196 (1.1) | 528 (3.3) | 575 (4.1) |
Soft tissue | C45-C49 | 162 (0.9) | 104 (0.6) | 188 (1.2) | 131 (0.9) |
Bone | C40-C41 | 130 (0.7) | 66 (0.4) | 185 (1.2) | 89 (0.6) |
Breast | C50 | 4950 (26.6) | 6038 (34.3) | N/A | N/A |
Cervical/uterine | C53-C55 | 2413 (12.9) | 2276 (12.9) | N/A | N/A |
Ovarian | C56 | 1247 (6.7) | 1202 (6.8) | N/A | N/A |
Testicular | C62-C63 | N/A | N/A | 4043 (25.2) | 1569 (11.2) |
Prostate | C61 | N/A | N/A | 600 (3.7) | 1643 (11.8) |
Other or unknown | C76-C80, C88 and othersd | 187 (1.0) | 218 (1.2) | 294 (1.8) | 285 (2.0) |
Stage of cancer at diagnosis | |||||
Local | N/A | 10030 (53.8) | 8828 (50.1) | 7870 (49.1) | 6244 (44.7) |
Regional | N/A | 4623 (24.8) | 4993 (28.3) | 2741 (17.1) | 2540 (18.2) |
Metastatic | N/A | 1399 (7.5) | 1969 (11.2) | 1779 (11.1) | 2138 (15.3) |
Unknowne | N/A | 2590 (13.9) | 1833 (10.4) | 3645 (22.7) | 3047 (21.8) |
Age of child at diagnosis | |||||
0 y | N/A | 656 (3.5) | 201 (1.1) | 680 (4.2) | 185 (1.3) |
1–4 y | N/A | 3647 (19.6) | 1252 (7.1) | 2959 (18.5) | 947 (6.8) |
5–9 y | N/A | 4877 (26.2) | 2513 (14.3) | 3566 (22.2) | 1695 (12.1) |
10–14 y | N/A | 3377 (18.1) | 2985 (16.9) | 2274 (14.2) | 2052 (14.7) |
≥15 y | N/A | 1714 (9.2) | 9737 (55.3) | 1321 (8.2) | 8048 (57.6) |
Born 1–4 y after diagnosis | N/A | 1547 (8.3) | 387 (2.2) | 1808 (11.3) | 442 (3.2) |
Born ≥5 y after diagnosis | N/A | 2824 (15.1) | 548 (3.1) | 3427 (21.4) | 600 (4.3) |
Notes:
Minor children are those aged between 0 and 18 y;
YA children are those aged between 19 and 25 y;
number of minor and YA children with parents with cancer;
not otherwise specified;
includes parental cancers with unknown stage and leukemias and around 50% of the lymphomas for which no stage was recorded.
Abbreviations: ICD-10, International Classification of Diseases, 10th edition; N/A, not applicable; y, years; YA, young adult.