Table 4.

Estimates from logistic regression models of characteristics impacting the likelihood of parental death from cancer among children with parents with cancer

Variable	Minor childrena		YA childrenb
	Cancer in father OR (95% CI)	Cancer in mother OR (95% CI)	Cancer in father OR (95% CI)	Cancer in mother OR (95% CI)
Cancer site
Other or unknownc	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
Colorectal	3.0 (2.4–3.6)	1.6 (1.2–2.0)	3.1 (2.6–3.6)	1.1 (0.9–1.4)
Skin	1.3 (1.0–1.6)	0.4 (0.3–0.5)	1.3 (1.1–1.6)	0.3 (0.3–0.4)
Brain	4.5 (3.6–5.6)	1.2 (1.0–1.6)	5.2 (4.3–6.3)	1.5 (1.2–1.9)
Lymphoma	0.5 (0.4–0.6)	0.3 (0.2–0.4)	1.2 (1.0–1.4)	0.4 (0.3–0.5)
Lung	6.9 (5.4–8.9)	3.8 (2.7–5.3)	11.5 (9.3–14.2)	4.7 (3.5–6.2)
Head and neck	1.8 (1.3–2.3)	0.6 (0.3–0.9)	1.6 (1.2–2.0)	0.7 (0.5–0.9)
Renal/bladder	1.4 (1.1–1.8)	Other	1.3 (1.1–1.6)	Other
Leukemia	2.3 (1.8–3.0)	Other	4.6 (3.7–5.8)	Other
Testicular	0.1 (0.1–0.2)	N/A	0.2 (0.2–0.3)	N/A
Endocrine	Other	0.1 (0.1–0.2)	Other	0.1 (0.1–0.2)
Breast	N/A	0.7 (0.6–0.9)	N/A	0.9 (0.7–1.1)
Cervical/uterine	N/A	0.4 (0.3–0.5)	N/A	0.5 (0.4–0.6)
Ovarian	N/A	0.2 (0.2–0.3)	N/A	0.3 (0.2–0.3)
Stage of cancer at diagnosis
Local	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
Regional	3.3 (2.8–3.8)	4.3 (3.7–4.9)	2.7 (2.3–3.1)	3.6 (3.2–4.0)
Metastatic	21.4 (18.0–25.5)	25.5 (21.1–30.7)	17.0 (14.6–19.7)	35.5 (29.9–42.1)
Unknown	2.0 (1.7–2.3)	1.8 (1.5–2.2)	1.8 (1.6–2.1)	2.8 (2.4–3.3)
Cancers (n)
1	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
≥2	2.1 (1.6–2.7)	1.6 (1.3–2.0)	1.9 (1.6–2.3)	1.9 (1.7–2.3)
Year of diagnosis
Before 1975	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
1975–1984	0.9 (0.5–1.6)	0.7 (0.3–1.6)	2.0 (1.2–3.1)	4.2 (2.1–8.4)
1985–1994	2.2 (1.3–3.7)	3.5 (1.7–7.5)	2.8 (1.8–4.4)	7.7 (4.0–15.2)
1995–2004	2.2 (1.3–3.6)	3.4 (1.6–7.2)	1.9 (1.2–2.9)	3.6 (1.8–7.1)
2005 or later	0.9 (0.6–1.6)	1.3 (0.6–2.7)	0.7 (0.4–1.1)	1.3 (0.7–2.6)
Age of parent at diagnosis: minor child (YA child)
<20 (<30) y	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
20–29 (30–39) y	0.7 (0.6–0.9)	1.2 (0.9–1.4)	1.1 (0.9–1.3)	1.1 (0.9–1.3)
30–39 (40–49) y	1.4 (1.2–1.6)	1.8 (1.5–2.1)	1.1 (0.9–1.3)	1.0 (0.9–1.1)
40–49 (50–59) y	1.4 (1.2–1.7)	1.3 (1.1–1.5)	1.1 (0.9–1.3)	0.8 (0.7–0.9)
≥50 (≥60) y	1.4 (1.1–1.7)	0.8 (0.6–1.1)	1.2 (1.0–1.5)	0.9 (0.6–1.4)
SES of parent: marital status
Not married	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
Married	1.0 (0.9–1.1)	1.0 (0.9–1.1)	0.9 (0.81–0.99)	1.0 (0.91–1.10)
SES of parent: children (n)
1	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
2	0.6 (0.5–0.8)	0.8 (0.7–0.9)	0.7 (0.6–0.8)	0.8 (0.7–0.9)
3	0.6 (0.5–0.7)	0.8 (0.7–0.9)	0.7 (0.6–0.8)	0.8 (0.7–0.9)
≥4	0.6 (0.5–0.8)	0.8 (0.6–0.9)	0.6 (0.5–0.8)	0.8 (0.7–0.9)
SES of parent: education level
Elementary school	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
High school	0.9 (0.8–1.1)	1.1 (0.9–1.2)	0.9 (0.8–0.9)	1.0 (0.9–1.2)
Some college	0.8 (0.7–0.9)	0.7 (0.6–0.8)	0.7 (0.6–0.8)	0.6 (0.5–0.7)
Bachelor’s degree	0.6 (0.5–0.7)	0.6 (0.5–0.7)	0.7 (0.6–0.8)	0.7 (0.6–0.8)
Master’s degree or higher	0.7 (0.6–0.9)	0.5 (0.4–0.7)	0.8 (0.7–0.9)	0.7 (0.5–0.8)
SES of parent: income/$10,000	0.9 (0.9–0.9)	0.9 (0.9–0.9)	0.9 (0.9–0.9)	0.9 (0.9–0.9)
Birth year: minor child (YA child)
Before 1995 (1983)	1.0 (ref)	1.0 (ref)	1.0 (ref)	1.0 (ref)
1995–1999 (1984)	0.8 (0.7–0.9)	0.8 (0.7–0.9)	0.9 (0.8–1.1)	1.1 (0.9–1.3)
2000–2004 (1985)	0.6 (0.5–0.7)	0.6 (0.5–0.7)	1.0 (0.8–1.1)	0.9 (0.8–1.0)
2005 or later (1986 or later)	0.2 (0.2–0.3)	0.3 (0.3–0.4)	0.8 (0.7–0.8)	0.9 (0.8–0.9)

Notes:

^aMinor children are those aged between 0 and 18 y;

^bYA children are those aged between 19 and 25 y;

^cincludes unknown cancer sites and those not listed;

^dincludes missing.

Abbreviations: CI, confidence interval; N/A, not applicable; OR, odds ratio; SES, socioeconomic status; y, years; YA, young adult.