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. 2012 Mar 9;8:105–130. doi: 10.2147/TCRM.S29830

Table G.

Adjusted indirect comparison of the proportion of patients achieving a sustained virologic response, relapsing to treatment, or discontinuing treatment at any point in a 48-week treatment course using boceprevir or telaprevir

Boceprevir Telaprevir Relative risk (95% CI) P value
Sustained virologic response
Patients
 Naïve 1.65 (1.43–1.91) 1.64 (1.50–1.79) 1.01 (0.85–1.19) 0.94
 Experienced 2.98 (2.29–3.87) 3.88 (3.05–4.94) 0.77 (0.54–1.10) 0.15
Relapse
Patients
 Naïve 0.42 (0.28–0.61) 0.30 (0.22–0.39) 1.40 (0.86–2.28) 0.18
 Experienced 0.40 (0.26–0.62) 0.22 (0.17–0.29) 1.82 (1.09–3.03) 0.02
Discontinuation
Patients
 Naïve 0.75 (0.64–0.88) 0.75 (0.45–1.23) 1.00 (0.59–1.69) 1.00
 Experienced 0.52 (0.44–0.60) 0.60 (0.47–0.77) 0.87 (0.65–1.16) 0.34

Abbreviation: CI, confidence interval.