Table 2. Passive immunization of NY1DD mice with anti-CXCL12, as compared to appropriate control F(ab)2 antibodies does not alter the extravasation of populations of other leukocytes into the lungs of these mice under baseline conditions.
Positive cells/Right Lung (×105) | |||
Anti-CXCL12 F(ab)2 | Control IgG F(ab)2 | ||
CD3 T-cells | CD3+ | 17.2+/−2.3 | 19.8+/−0.62 |
CD4 T-cells | CD3+ CD4+ | 6.6+/−0.61 | 8.2+/−0.99 |
CD8 T-cells | CD3+ CD8+ | 7.1+/−1.1 | 8.6+/−0.59 |
NK cells | CD3+ NK1.1+ | 6.1+/−0.31 | 9.5+/−1.4 |
Neutrophils | CD11b+ Ly6g+ | 21.4+/−1.5 | 28.3+/−2.1 |
Macrophages | MAC3+CD11b-CD11c+ | 23.3+/−2.5 | 26.6+/−4.2 |