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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Biol Psychiatry. 2012 Jan 20;71(7):642–651. doi: 10.1016/j.biopsych.2011.11.028

Figure 5.

Figure 5

The effects of testosterone on the mRNA expression of brain derived neurotrophic factor (BDNF), glucocorticoid receptor (GR), and extracellular signal regulated kinase (ERK2) in the hippocampus of adult male sham gonadectomized (n=9–12), or gonadectomized animals receiving placebo (n=7–9), low (n=5–6), or high dose supplementation (n=6–7). Testosterone levels do not significantly affect mRNA expression of (A) BDNF or (B) GR, but (C) positively regulate ERK2 expression in the hippocampus. *p<0.05 compared to sham; #p<0.05 compared to placebo; Gnx = gonadectomized.