Table 1.
Childhood (LRC) and young adult (PFS) cardiovascular risk factors in 852 children from 519 families1
| Mean ±SD at LRC | Mean ±SD at PFS | Spearman correlations (values at LRC and PFS) | |
|---|---|---|---|
| Race | W 631 (74%), B 221 (26%) | ||
| Gender | M 396 (46%), F 456 (54%) | ||
| Age (yr) | 12.3 ±3.4 | 38.6 ±3.7 | |
| TG (mg/dl) | 77 ±37 | 136 ±131 | r =0.35, p<.0001 |
| HDLC (mg/dl) | 55 ±12 | 45 ±15 | r =0.47, p<.0001 |
| LDLC (mg/dl) a | 105 ±28 | 121 ±35 | r =0.51, p<.0001 |
| LDL/HDL a | 2.02 ±0.74 | 2.95 ±1.33 | r =0.48, p<.0001 |
| SBP (mmHg) b | 103 ±12 | 119 ±15 | r=0.22, p<.0001 |
| DBP (mmHg) b | 62 ±12 | 78 ±11 | r=0.19, p<.0001 |
| BMI (kg/m2) | 20.0 ±4.3 | 28.6 ±6.9 | r =0.39, p<.0001 |
| Glucose (mg/dl) | 85 ±8 | 90 ±23 | r =0.17, p<.0001 |
| Young adult (LRC) and older adult (PFS) cardiovascular risk factors in 422 parents who had measures at LRC and at PFS | |||
| Mean ±SD at LRC | Mean ±SD at PFS | Spearman correlations | |
| Race | W 335 (79%), B 87 (21%) | ||
| Gender | M 165 (39%), F 257 (61%) | ||
| Age (yr) | 39.5 ±6.5 | 66.4 ±6.5 | |
| TG (mg/dl) | 125 ±76 | 153 ±94 | r =0.43, p<.0001 |
| HDLC (mg/dl) | 53 ±14 | 46 ±15 | r =0.63, p<.0001 |
| LDLC (mg/dl) a | 125 ±32 | 128 ±34 | r =0.44, p<.0001 |
| LDL/HDL a | 2.48 ±1.03 | 2.94 ±1.19 | r =0.57, p<.0001 |
| SBP (mmHg) b | 113 ±11 | 134 ±18 | r =0.20, p=.045 |
| DBP (mmHg) b | 75 ±9 | 78 ±11 | r =0.11, p=.28 |
| BMI (kg/m2) | 26.3 ±4.9 | 30.0 ±6.2 | r =0.65, p<.0001 |
| Glucose (mg/dl) | 90 ±14 | 105±37 | r =0.37, p<.0001 |
1
(had information of CVD status on father and mother)
a
excluded cholesterol lowering medication users (31 [4%] offspring, 148 [35%] parents)
b
excluded BP lowering medication users (63 [7%] offspring, 222 [53%] parents)