Table 3.
Parental outcome | Pediatric Predictors | OR, [95% CI], p |
---|---|---|
CVD ≤age 50 (62 Yes, 390 no) 452 observations used AUC=0.628 | TG at LRC, unit=10mg/dl | 1.11, [1.04-1.18], p=.002 |
CVD ≤age 60 (128 Yes, 324 no) 452 observations used AUC=0.614 | TG at LRC, unit=10mg/dl | 1.11, [1.05-1.18], p=.0004 |
CVD any age (211 Yes, 241 no) 452 observations used AUC=0.634 | TG at LRC, unit=10mg/dl | 1.07, [1.001-1.13], p=.048 |
LDLC at LRC, unit=10mg/dl | 1.10, [1.03-1.19], p=.008 | |
Age at LRC, unit=year | 1.11, [1.03-1.19], p=.004 | |
T2DM (162 Yes, 285 no) 447 observations used AUC=0.591 | BMI at LRC, unit=5kg/m2 | 1.38, [1.08-1.77], p=.01 |
Hypertension (299 Yes, 134 no) 433 observations used AUC=0.684 | DBP at LRC, unit=10 mmHg | 1.41, [1.17-1.71], p=.0004 |
Sex (Male=1, Female=2) | 1.88, [1.16-3.03], p=.01 | |
Race (White=1, Black=2) | 2.38, [1.37-4.13], p=.002 | |
Number of siblings | 1.70, [1.29-2.26], p=.0002 |
Stepwise selection from explanatory variables: race and mean value of offspring’s pediatric measures at LRC: age, sex, BMI, SBP, DBP, TG, HDLC, LDLC, glucose, maturation stage, and number of siblings