Table VII.
Correlations between midvalues of parents and midvalues of offspring’s risk factors (TG, HDLC, LDLC, LDLC/HDLC, SBP, DBP, BMI, Glucose) in 95 families with measures on father, mother, and ≥ 1 offspring
| Schoolchildren mean ±SD | Parents mean ±SD | Correlations between children and their parents | ||
|---|---|---|---|---|
| At LRC | ||||
|
| ||||
| Age (yr) | 12.2 ±3.1 | 39.3 ±5.5 | ||
|
| ||||
| TG (mg/dl) | 82 ±36 | 126 ±48 | r=0.40, p<.0001 | |
|
| ||||
| HDLC (mg/dl) | 55 ±10 | 53 ±11 | r=0.56, p<.0001 | |
|
| ||||
| LDLC (mg/dl) | 101 ±24 | 135 ±26 | r=0.40, p<.0001 | |
|
| ||||
| LDL/HDL | 1.91 ±0.60 | 2.76 ±0.75 | r=0.48, p<.0001 | |
|
| ||||
| SBP (mmHg) | 106 ±12 | 121 ±15 | r= -0.05, p=.76 | |
|
| ||||
| DBP (mmHg) | 62 ±13 | 80 ±11 | r= -0.06, p=.71 | |
|
| ||||
| BMI (kg/m2) | 20.3 ±4.1 | 26.2 ±3.3 | r=0.33, p=.0024 | |
|
| ||||
| Glucose (mg/dl) | 85 ±8 | 90 ±9 | r=0.47, p<.0001 | |
|
| ||||
| At PFS | Correlations between children at PFS (median age 39) and parents at LRC (median age 39) | |||
|
| ||||
| Age (yr) | 38.8 ±3.4 | 66.2 ±5.6 | ||
|
| ||||
| TG (mg/dl) | 136 ±81 | 147 ±55 | r=0.32, p=.0016 | r=0.38, p=.0002 |
|
| ||||
| HDLC (mg/dl) | 46 ±14 | 45 ±10 | r=0.31, p=.0020 | r=0.37, p=.0004 |
|
| ||||
| LDLC (mg/dl) | 118 ±28 | 118 ±27 | r=0.29, p=.0044 | r=0.25, p=.018 |
| 113 ±29a | 131 ±27 a | r=0.42, p=.0053 a | ||
|
| ||||
| LDL/HDL | 2.89 ±1.03 | 2.87 ±0.85 | r=0.17, p=.095 | r=0.28, p=.0071 |
| 2.71 ±1.00 a | 3.13 ±0.95 a | r=0.22, p=.16 a | ||
|
| ||||
| SBP (mmHg) | 119 ±12 | 136 ±13 | r= 0.31, p=.0019 | r= -0.0068, p=.96 |
| 112 ±9 b | 129 ±16 b | r=0.29, p=.12 b | ||
|
| ||||
| DBP (mmHg) | 78 ±9 | 77 ±8 | r= 0.22, p=.029 | r= -0.054, p=.69 |
| 74 ±7 b | 74 ±11 b | r=0.38, p=.038 b | ||
|
| ||||
| BMI (kg/m2) | 27.2 ±4.8 | 29.4 ±4.3 | r=0.44, p<.0001 | r=0.42, p<.0001 |
|
| ||||
| Glucose (mg/dl) | 88 ±18 | 103±28 | r=0.40, p<.0001 | r=0.25, p=.020 |
a
excluded parents (n=68) and schoolchildren (n=2) taking lower-cholesterol medication at PFS
b
excluded parents (n=92) and schoolchildren (n=12) taking lower-BP medication at PFS