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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Feb 7;1825(2):229–244. doi: 10.1016/j.bbcan.2012.01.004

Figure 4. The p53 family of transcription factors.

Figure 4

Schematic of the gene architecture and well characterized isoforms of p53 and the closely related factors p63 and p73. Arrows represent alternative promoters, boxes represent exons (black segments are untranslated regions). TAD: transactivaiton domain. TA2: second transactivation domain. PY: proline rich domain. DBD: DNA binding domain. NLS: nuclear localization signal. OD: oligomerization domain. SAM: sterile-alpha motif. TID: trans-inhibitory domain.