. Author manuscript; available in PMC: 2013 Mar 19.

Published in final edited form as: Chem Res Toxicol. 2012 Feb 21;25(3):730–740. doi: 10.1021/tx200531y

Table 2.

dG^AP bypass efficiencies of human Y-family DNA polymerases.

Enzyme	t₅₀^bypass (s)^a	t₅₀ (s)^b	t₅₀^bypass/t₅₀
hPolη	2.5	0.8	3.1
hPolκ	4.1	1.5	2.7
hPolτ	107	15	7.1

Calculated as the time required to bypass 50% of the dG^AP sites.

Calculated as the time required to bypass 50% of dG, or 20-mer.