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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Jan 14;1820(4):532–541. doi: 10.1016/j.bbagen.2012.01.003

Figure 4.

Figure 4

A mitochondrial damage and recovery profile interposed on a hypothetical timeline between an acute inflammatory insult and a subsequent period of immune suppression. The diagram indicates the nomenclature for the systemic inflammatory response and the compensatory anti-inflammatory response used most conspicuously in bacterial sepsis to describe hyper-activation of innate immunity followed by an extended period of immune suppression. The risk of secondary or recurrent infection is increased during the period of immune suppression.