Figure 3. Effect of sterculic acid on the 7KCh-mediated mRNA induction of inflammatory cytokines and ER stress markers.
ARPE-19 cells were treated simultaneously with 8 μM 7KCh and 1 μM sterculic acid, 1 μM stearic acid, or the combinations of 7KCh with either sterculic acid or stearic acid (negative control). The mRNA expression (mean ± s.d., n = 4) of inflammatory cytokines (VEGF, IL-1β, IL-6, IL-8, TNFα, TGF-1β) and ER stress markers (GRP78 and CHOP) was measure by qRT-PCR 24 h after treatment. *p < 0.05 comparing to 7KCh, two-tailed Student’s t-test.