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Copy number variation profile of the p38 pathway
| Gene symbol | Tumor | Normal |
|---|---|---|
| Amplified genes | ||
| HSP27 | 21% | 2% |
| CREB1 | 27% | 16% |
| TCF3 | 14% | 2% |
| ER81 | 45% | 6% |
| CDC25B | 36% | 20% |
| Deleted genes | ||
| MAPKAPK3 | 20% | 11% |
| LSP1 | 31% | 25% |
| TH | 37% | 14% |
| YWHAZ | 63% | 27% |
| ALOX5 | 68% | 7% |
| RAF1 | 13% | 9% |
Of the 13 genes in the p38 pathway, 11 show significant change (according to Mann-Whitney U test) in copy number, amplification or deletion, between the tumor and its matched normal sample across all patients.
