Figure 4.
Therapeutic effects of hUCB-MSC administration on recovery in the ischemic animal model. Performance in the (a) Rotarod and (b) adhesive removal tests from 1 to 28 days after ischemia. The data were collected from seven animals per group and are presented as mean values ± SD. (c) Brain slices were stained with TTC at seven days after PBS or 1 × 106 hUCB-MSC administration to visualize lesions. (d) The data were collected from five animals per group and are presented as mean relative infarct volume ± SD. Statistically significant differences between the groups were determined by analysis of variance (*P < 0.05 compared with the PBS injected group intrathecally; #P < 0.05 compared with the PBS injected group intravenously).