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Methods to quantify bone changes in the hands and vertebrae. (a) Methods to quantify periarticular bone changes. (b) Methods to quantify vertebral bone changes. μCT, micro-computed tomography; DXA, dual-energy x-ray absorptiometry; DXR, digitalized radiogrammetry; HRDR, high-resolution digital radiology; MRI, magnetic resonance imaging; QCT, quantitative computer tomography; QUS, quantitative ultrasound; VFA, vertebral fracture assessment.
