Table 2.
Shared epitope classification according to amino acid sequence at positions 70-74
| Allele classification | Amino acid sequence positions 70 to 74 | HLA-DRB1 alleles |
|---|---|---|
| S1 | D-E-RAA | *01:03, *04:02, *11:02-:03, *13:01-:02, *13:04, *13:36, *13:40 |
| Q-A-RAA | *15 | |
| S2 | Q-K-RAA | *04:01, *04:09, *04:13, *04:35, *04:66 |
| D-K-RAA | *13:03 | |
| S3D | D-R-RAA | *11:01, *11:04, *11:27, *12, *13:05-:06, *13:25, *14:22, *16 |
| S3P | Q-R-RAA | *01:01-:02, *04:04-:05, *04:08, *04:10 |
| R-R-RAA | *10:01 | |
| X | Q-K-RGR | *03 |
| Q-R-RAE | *04:03, *04:07, *04:11 | |
| D-R-RGQ | *07 | |
| D-R-RAL | *08 | |
| R-R-RAE | *09:01, *14:01, *14:04 |
HLA = human leucocyte antigen. Data in right column from Gao et al. [6].