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. 2011 Oct 13;13(5):R164. doi: 10.1186/ar3483

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Copyright ©2011 Lee et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Infiltration of chronic inflammatory cells in gouty tophus tissues. (a) Tophus tissue sections from patients with chronic gouty arthritis were processed for hematoxylin-eosin (HE) staining. * indicates monosodium urate monohydrate (MSU) crystals, and ** represents osteolytic lesions. (b) Serial sections were processed for immunohistochemical staining using anti-CD3, anti-CD4, anti-CD8, anti-CD20, anti-CD68, and anti-c-kit antibodies (brown). Scale bar in a = 500 μm; scale bars in b = 50 μm.