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. 2011 Oct 21;13(5):R172. doi: 10.1186/ar3495

Table 3.

Coincidence* of autoantibodies in 863 individual systemic sclerosis patients

Antibodies ACA ATA Anti-PM-Scl Anti-U1-RNP Anti-RNAP Anti-fibrilla-rin Anti-To Anti-Ku Anti-Jo-1/Pl-7/OJ Anti-U11-RNP Anti-Ro52 Anti-Ro60 Anti-La AMA Anti-p25/p23 Anti-NOR-90 Anti-SL Anti-Sm Anti-Sp100 Other
ACA 1 0 1 0 0 0 0 0 0 92 11 1 31 28 4 2 0 3 144
ATA 1 2 0 0 0 4 0 0 36 26 6 4 0 1 4 1 0 77
Anti-PM-Scl 0 0 0 0 1 0 0 6 2 0 0 0 0 0 0 0 4
Anti-U1-RNP 1 0 0 0 0 0 11 6 1 2 0 1 0 4 0 11
Anti-RNAP 0 0 0 0 0 5 1 1 1 0 0 1 0 0 5
Anti-fibrillarin 0 0 0 0 0 0 0 1 0 0 0 0 0 8
Anti-To 0 0 0 1 1 0 0 0 0 0 0 0 2
Anti-Ku 0 0 2 2 0 0 0 0 1 0 0 2
Anti-Jo-1/Pl-7/OJ 0 3 0 0 0 0 0 0 0 0 1
Anti-U11-RNP 0 0 0 0 0 0 0 0 0 0
Anti-Ro52 41 15 14 11 2 5 2 2 97
Anti-Ro60 14 6 0 0 0 1 1 33
Anti-La 1 0 0 0 1 0 8
AMA 2 0 1 1 2 29
Anti-p25/p23 1 1 0 1 18
Anti-NOR-90 0 1 0 4
Anti-SL 0 0 3
Anti-Sm 0 0
Anti-Sp100 2
Other
Isolateda 104 153 31 19 23 4 0 4 1 1 2 1 0 0 0 0 1 0 0 79
Totalb 310 260 42 41 33 12 2 10 4 1 187 59 16 41 28 6 9 4 4 363

*Number of patients with co-occurrences of autoantibodies. aIsolated: presence without coincidence of any other autoantibody by all detection methods used. bTotal number of individuals with the respective autoantibody; these numbers mostly are smaller than the sum of all co-occurrences plus the 'isolated' individuals listed because of some triple, quadruple and higher-order coincidences. ACA = anti-centromere antibodies; AMA = antimitochondrial antibodies; ATA = anti-topoisomerase I antibodies;; RNAP = RNA polymerase; RNP = ribonucleoprotein.