Figure 6. Electrostatic surface diagrams of the three FAEs used in enrichment and rank-ordering studies.

The binding cavity is depicted in gren mesh and the volume of binding pocket is depicted as green trasparent sphere. It is evident from the diagrams that the volume of binding cavity of TsFAEC is very large that allows high degree of freedom for flexible docking algorithms for posing the ligands. (a) AnFAEA. (b) AnFAEB. (c) TsFAEC.